Assay Detail

CHEMBL4334156

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Cytotoxicity against human MGC cells after 48 hrs by CCK8 assay

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Prenylated Indole Diterpene Alkaloids from a Mine-Soil-Derived Tolypocladium sp.

Xu LL, Hai P, Zhang SB, Xiao JF, Gao Y, Ma BJ, Fu HY, Chen YM, Yang XL.
J Nat Prod (2019) 82 : 221 -231
PubMed 30702286 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	7.14	9.49

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL65	CAMPTOTHECIN	-1.0	1	9.49
CHEMBL4474426	—	—	1	4.79

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL65	CAMPTOTHECIN	IC50	=	0.32	nM	9.49
CHEMBL4474426	—	IC50	=	16320.0	nM	4.79