Assay Detail
Functional
CHEMBL4334322
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Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-MEL-28 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Advance of Seriniquinone Analogues as Melanoma Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.73 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4450400 | — | — | 1 | 6.48 |
| CHEMBL4438542 | — | — | 1 | 6.44 |
| CHEMBL4476574 | — | — | 1 | 5.75 |
| CHEMBL4576074 | — | — | 1 | 5.67 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.52 |
| CHEMBL4437459 | — | — | 1 | 5.46 |
| CHEMBL4554800 | — | — | 1 | 5.37 |
| CHEMBL4474312 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4450400 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL4438542 | — | IC50 | = | 360.0 | nM | 6.44 |
| CHEMBL4476574 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL4576074 | — | IC50 | = | 2150.0 | nM | 5.67 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL4437459 | — | IC50 | = | 3470.0 | nM | 5.46 |
| CHEMBL4554800 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL4474312 | — | IC50 | = | 7000.0 | nM | 5.16 |