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Assay Detail

CHEMBL4334781

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human H460 cells incubated for 4 days by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NCI-H460
Confidence 1 — Organism
Curated By Autocuration

Target

NCI-H460 (CHEMBL396)
Type CELL-LINE
Organism Homo sapiens

Publication

A cell-based screening system for RNA polymerase I inhibitors.
Tan X, Awuah SG.
Medchemcomm (2019) 10 : 1765 -1774
PubMed 31803394 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.46 5.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1200563 CERIVASTATIN SODIUM 4.0 1 5.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1200563 CERIVASTATIN SODIUM IC50 = 3500.0 nM 5.46