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Assay Detail

CHEMBL4335387

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against RSV infected in African green monkey Vero cells assessed as inhibition of viral replication measured after 5 to 7 days by plaque formation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Respiratory syncytial virus
Cell Type Vero
Confidence 1 — Organism
Curated By Autocuration

Target

Respiratory syncytial virus (CHEMBL612679)
Type ORGANISM
Organism Respiratory syncytial virus

Publication

Discovery, Optimization, and Target Identification of Novel Potent Broad-Spectrum Antiviral Inhibitors.
Yang Y, Cao L, Gao H, Wu Y, Wang Y, Fang F, Lan T, Lou Z, Rao Y.
J Med Chem (2019) 62 : 4056 -4073
PubMed 30938999 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.22 7.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4454780 1 7.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4454780 EC50 = 60.0 nM 7.22