Assay Detail
Functional
CHEMBL4335606
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against BCR-ABL p185-positive mouse B-ALL cells overexpressing human BFL-1 assessed as inhibition of cell viability after 24 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B-ALL |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Studies of Jatrogossone A as a Reactive Oxygen Species Inducer in Cancer Cellular Models.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.37 | 5.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4217960 | — | — | 1 | 5.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4217960 | — | IC50 | = | 4265.0 | nM | 5.37 |