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Assay Detail

CHEMBL4335609

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against BCR-ABL p185-positive mouse B-ALL cells transfected with empty vector assessed as inhibition of cell viability after 24 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type B-ALL
Confidence 1 — Organism
Curated By Autocuration

Target

B-ALL (CHEMBL4483287)
Type CELL-LINE

Publication

Studies of Jatrogossone A as a Reactive Oxygen Species Inducer in Cancer Cellular Models.
Ling T, Lang WH, Craig J, Potts MB, Budhraja A, Opferman J, Bollinger J, Maier J, Marsico TD, Rivas F.
J Nat Prod (2019) 82 : 1301 -1311
PubMed 31084028 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.34 5.34

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4217960 1 5.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4217960 IC50 = 4567.0 nM 5.34