Assay Detail
Binding
CHEMBL4336199
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human MARK4 incubated for 2 hrs by [gamma32P]ATP assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
MAP/microtubule affinity-regulating kinase 4 (CHEMBL5754) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of α-Mangostin as a Potential Inhibitor of Microtubule Affinity Regulating Kinase 4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.75 | 5.75 |
| Inhibition | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL323197 | MANGOSTIN | — | 2 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL323197 | MANGOSTIN | IC50 | = | 1770.0 | nM | 5.75 |
| CHEMBL323197 | MANGOSTIN | Inhibition | - | % | - |