Assay Detail
Binding
CHEMBL4336749
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Inhibition of FAP (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Integrated Synthetic, Biophysical, and Computational Investigations of Covalent Inhibitors of Prolyl Oligopeptidase and Fibroblast Activation Protein α.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.44 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1243126 | — | — | 1 | 7.70 |
| CHEMBL67279 | TALABOSTAT | 3.0 | 1 | 7.18 |
| CHEMBL2333026 | — | — | 1 | - |
| CHEMBL4464623 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1243126 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL67279 | TALABOSTAT | IC50 | = | 66.0 | nM | 7.18 |
| CHEMBL2333026 | — | IC50 | > | 36.0 | nM | - |
| CHEMBL4464623 | — | IC50 | > | 100000.0 | nM | - |