Assay Detail
Binding
CHEMBL4336764
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Inhibition of CK2alpha in human PLC1 cells using (Arg)3(Glu)3Thr(Glu)3 as substrate after 24 hrs in presence of [32P]gammaGTP
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Small molecule modulators targeting protein kinase CK1 and CK2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.42 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL373937 | — | — | 1 | 7.40 |
| CHEMBL177820 | TETRABROMOBENZOTRIAZOLE | — | 1 | 6.52 |
| CHEMBL3706697 | — | — | 1 | 6.40 |
| CHEMBL376505 | — | — | 1 | 5.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL373937 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL177820 | TETRABROMOBENZOTRIAZOLE | Ki | = | 300.0 | nM | 6.52 |
| CHEMBL3706697 | — | Ki | = | 400.0 | nM | 6.40 |
| CHEMBL376505 | — | Ki | = | 4500.0 | nM | 5.35 |