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Assay Detail

CHEMBL4337203

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Binding
Inhibition of human MAOA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] A (CHEMBL1951)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Multi-target-directed-ligands acting as enzyme inhibitors and receptor ligands.
Rodríguez-Soacha DA, Scheiner M, Decker M.
Eur J Med Chem (2019) 180 : 690 -706
PubMed 31401465 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 7.10 9.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1929421 1 9.52
CHEMBL4173258 1 6.84
CHEMBL14638 CIPROXIFAN 1 4.94

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1929421 IC50 = 0.3 nM 9.52
CHEMBL4173258 IC50 = 145.0 nM 6.84
CHEMBL14638 CIPROXIFAN IC50 = 11400.0 nM 4.94