Assay Detail
Binding
CHEMBL4337570
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HDAC1/2 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Histone deacetylase (HDAC1 and HDAC2) (CHEMBL2111429) ↗| Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
Publication
14- and 15-membered lactone macrolides and their analogues and hybrids: structure, molecular mechanism of action and biological activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.56 | 8.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL472250 | — | — | 1 | 8.72 |
| CHEMBL455735 | — | — | 1 | 8.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL472250 | — | IC50 | = | 1.9 | nM | 8.72 |
| CHEMBL455735 | — | IC50 | = | 4.1 | nM | 8.39 |