Assay Detail
Binding
CHEMBL4338738
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human neurotensin receptor 1 stably expressed in CHO cells preincubated for 20 mins to 2 hrs followed by addition of NT (8 to 13) measured upto 180 mins by FACSCalibur flow cytometry analysis
8
Total Activities
8
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Fluorescence Labeling of Neurotensin(8-13) via Arginine Residues Gives Molecular Tools with High Receptor Affinity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| pKd | 6 | - | - |
| Kd | 2 | 8.43 | 8.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4564746 | — | — | 1 | 8.44 |
| CHEMBL4457798 | — | — | 1 | 8.41 |
| CHEMBL4534768 | — | — | 1 | - |
| CHEMBL4584647 | — | — | 1 | - |
| CHEMBL4537266 | — | — | 1 | - |
| CHEMBL4463399 | — | — | 1 | - |
| CHEMBL4592541 | — | — | 1 | - |
| CHEMBL4566971 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4564746 | — | Kd | = | 3.631 | nM | 8.44 |
| CHEMBL4457798 | — | Kd | = | 3.89 | nM | 8.41 |
| CHEMBL4534768 | — | pKd | - | — | - | |
| CHEMBL4584647 | — | pKd | - | — | - | |
| CHEMBL4537266 | — | pKd | - | — | - | |
| CHEMBL4463399 | — | pKd | - | — | - | |
| CHEMBL4592541 | — | pKd | - | — | - | |
| CHEMBL4566971 | — | pKd | - | — | - |