Assay Detail
Functional
CHEMBL4339588
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Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability measured after 72 hrs by MTS assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-468 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Optimization of Peptidomimetics as Selective Inhibitors for the β-Catenin/T-Cell Factor Protein-Protein Interaction.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.74 | 4.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4465565 | — | — | 1 | 4.97 |
| CHEMBL4451478 | — | — | 1 | 4.69 |
| CHEMBL4561695 | — | — | 1 | 4.57 |
| CHEMBL4460506 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4465565 | — | IC50 | = | 10600.0 | nM | 4.97 |
| CHEMBL4451478 | — | IC50 | = | 20600.0 | nM | 4.69 |
| CHEMBL4561695 | — | IC50 | = | 26900.0 | nM | 4.57 |
| CHEMBL4460506 | — | IC50 | > | 200000.0 | nM | - |