Assay Detail
Binding
CHEMBL4341998
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Inhibition of BMI1 promoter in HEK293T cells incubated for 24 hrs by luciferase reporter gene assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Identification of BMI1 promoter inhibitors from Streptomyces sp. IFM-11958.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.18 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3740707 | — | — | 1 | 7.52 |
| CHEMBL4441305 | — | — | 1 | 6.35 |
| CHEMBL505734 | NOCARDAMINE | — | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3740707 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL4441305 | — | IC50 | = | 447.0 | nM | 6.35 |
| CHEMBL505734 | NOCARDAMINE | IC50 | = | 22000.0 | nM | 4.66 |