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Assay Detail

CHEMBL4343147

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HDAC in human HeLa cell extracts
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HeLa
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Histone deacetylase (CHEMBL2093865)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Indole: A privileged scaffold for the design of anti-cancer agents.
Wan Y, Li Y, Yan C, Yan M, Tang Z.
Eur J Med Chem (2019) 183 : 111691 -111691
PubMed 31536895 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL408513 BELINOSTAT 4.0 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL408513 BELINOSTAT IC50 = 10.0 nM 8.00