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Assay Detail

CHEMBL4343322

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Functional
Antiproliferative activity against human K562-Lucena 1 cells assessed as reduction in cell viability after 24 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type K562-Lucena 1
Confidence 1 — Organism
Curated By Autocuration

Target

K562-Lucena 1 (CHEMBL4630704)
Type CELL-LINE
Organism Homo sapiens

Publication

1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
Xu Z, Zhao SJ, Liu Y.
Eur J Med Chem (2019) 183 : 111700 -111700
PubMed 31546197 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.84 4.84

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2022335 1 4.84
CHEMBL2022336 1 4.84

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2022335 IC50 = 14300.0 nM 4.84
CHEMBL2022336 IC50 = 14300.0 nM 4.84