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Assay Detail

CHEMBL4343620

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition OF SGLT2 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Sodium/glucose cotransporter 2 (CHEMBL3884)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthetic strategy and SAR studies of C-glucoside heteroaryls as SGLT2 inhibitor: A review.
Haider K, Pathak A, Rohilla A, Haider MR, Ahmad K, Yar MS.
Eur J Med Chem (2019) 184 : 111773 -111773
PubMed 31630053 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.65 8.65

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1093423 LUSEOGLIFLOZIN 2.0 1 8.65

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1093423 LUSEOGLIFLOZIN IC50 = 2.26 nM 8.65