Assay Detail
Functional
CHEMBL4343684
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Antiparasitic activity against Toxoplasma gondii RH transfected with fluorescent transgene dTom
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Toxoplasma gondii |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A new chemotype with promise against Trypanosoma cruzi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.39 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL36 | PYRIMETHAMINE | 4.0 | 1 | 6.10 |
| CHEMBL4589398 | — | — | 1 | 4.68 |
| CHEMBL3105168 | — | — | 1 | - |
| CHEMBL4564866 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL36 | PYRIMETHAMINE | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL4589398 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL3105168 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4564866 | — | IC50 | > | 100000.0 | nM | - |