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Assay Detail

CHEMBL4343846

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Autocuration

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

Artemisia: a promising plant for the treatment of cancer.
Taleghani A, Emami SA, Tayarani-Najaran Z.
Bioorg Med Chem (2020) 28 : 115180 -115180
PubMed 31784199 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.86 5.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL137803 ISOALANTOLACTONE 1 5.09
CHEMBL4535687 1 4.75
CHEMBL4472473 1 4.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL137803 ISOALANTOLACTONE IC50 = 8150.0 nM 5.09
CHEMBL4535687 IC50 = 17940.0 nM 4.75
CHEMBL4472473 IC50 = 17940.0 nM 4.75