Assay Detail
Binding
CHEMBL4344064
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Binding affinity to human CB1 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.26 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL465 | DRONABINOL | 4.0 | 1 | 7.40 |
| CHEMBL2387541 | TETRAHYDROCANNABIVARIN | 2.0 | 1 | 7.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL465 | DRONABINOL | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL2387541 | TETRAHYDROCANNABIVARIN | Ki | = | 75.4 | nM | 7.12 |