Assay Detail
Binding
CHEMBL4344280
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Activation of rat hepatocytes AMPK alpha1/beta1/gamma1 expressed in baculovirus infected Sf9 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | Sf9 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.39 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4167177 | — | — | 1 | 8.85 |
| CHEMBL3891221 | — | — | 1 | 8.15 |
| CHEMBL4082745 | — | — | 1 | 8.10 |
| CHEMBL4061943 | — | — | 1 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4167177 | — | EC50 | = | 1.4 | nM | 8.85 |
| CHEMBL3891221 | — | EC50 | = | 7.0 | nM | 8.15 |
| CHEMBL4082745 | — | EC50 | = | 8.0 | nM | 8.10 |
| CHEMBL4061943 | — | EC50 | = | 36000.0 | nM | 4.44 |