Assay Detail
Binding
CHEMBL4344284
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ACC2 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.45 | 8.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3407547 | FIRSOCOSTAT | 2.0 | 1 | 8.59 |
| CHEMBL4557289 | — | — | 1 | 8.52 |
| CHEMBL4567446 | CLESACOSTAT | 2.0 | 1 | 7.52 |
| CHEMBL4476176 | — | — | 1 | 5.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3407547 | FIRSOCOSTAT | IC50 | = | 2.6 | nM | 8.59 |
| CHEMBL4557289 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL4567446 | CLESACOSTAT | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL4476176 | — | IC50 | = | 6600.0 | nM | 5.18 |