Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4344296

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CCR7 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

C-C chemokine receptor type 7 (CHEMBL4594)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease.
Romero FA, Jones CT, Xu Y, Fenaux M, Halcomb RL.
J Med Chem (2020) 63 : 5031 -5073
PubMed 31930920 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.68 8.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL41275 1 8.85
CHEMBL2110727 CENICRIVIROC 3.0 1 8.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL41275 IC50 = 1.4 nM 8.85
CHEMBL2110727 CENICRIVIROC IC50 = 3.1 nM 8.51