Assay Detail
Binding
CHEMBL4344597
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Bacteroides fragilis GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacteroides fragilis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.23 | 8.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4589187 | — | — | 1 | 8.44 |
| CHEMBL4451253 | — | — | 1 | 5.44 |
| CHEMBL4441158 | — | — | 1 | 4.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4589187 | — | Ki | = | 3.6 | nM | 8.44 |
| CHEMBL4451253 | — | Ki | = | 3660.0 | nM | 5.44 |
| CHEMBL4441158 | — | Ki | = | 15480.0 | nM | 4.81 |