Assay Detail
Binding
CHEMBL4345200
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Binding affinity to wild type human full length RIOK1 (M1 to K568 residues) expressed in bacterial expression system by Kinomescan method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase RIO1 (CHEMBL5975) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.14 | 7.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4452939 | — | — | 1 | 7.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4452939 | — | Kd | = | 72.0 | nM | 7.14 |