Assay Detail
Binding
CHEMBL4346836
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]PSB-603 from recombinant mouse A2B adenosine receptor expressed in CHO cell membranes measured after 75 mins in presence of adenosine deaminase by liquid scintillation counting method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A<sub>2B</sub> Adenosine Receptor Antagonists with Picomolar Potency.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 9.01 | 9.88 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4552275 | — | — | 1 | 9.88 |
| CHEMBL4464522 | — | — | 1 | 9.04 |
| CHEMBL4466765 | — | — | 1 | 9.03 |
| CHEMBL4537196 | — | — | 1 | 8.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4552275 | — | Ki | = | 0.131 | nM | 9.88 |
| CHEMBL4464522 | — | Ki | = | 0.901 | nM | 9.04 |
| CHEMBL4466765 | — | Ki | = | 0.926 | nM | 9.03 |
| CHEMBL4537196 | — | Ki | = | 8.34 | nM | 8.08 |