Assay Detail
Binding
CHEMBL4346837
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Displacement of [3H]CCPA from recombinant mouse A1 adenosine receptor expressed in CHO cell membranes measured after 90 mins in presence of adenosine deaminase by liquid scintillation counting method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A<sub>2B</sub> Adenosine Receptor Antagonists with Picomolar Potency.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.40 | 6.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4464522 | — | — | 1 | 6.97 |
| CHEMBL4537196 | — | — | 1 | 5.82 |
| CHEMBL4466765 | — | — | 1 | - |
| CHEMBL4552275 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4464522 | — | Ki | = | 107.0 | nM | 6.97 |
| CHEMBL4537196 | — | Ki | = | 1520.0 | nM | 5.82 |
| CHEMBL4466765 | — | Ki | > | 300.0 | nM | - |
| CHEMBL4552275 | — | Ki | > | 1000.0 | nM | - |