Assay Detail
Functional
CHEMBL4348012
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human PANC1 cells incubated for 24 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PANC-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Multi-target compounds acting in cancer progression: Focus on thiosemicarbazone, thiazole and thiazolidinone analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.27 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL385064 | — | — | 1 | 8.40 |
| CHEMBL2203744 | — | — | 1 | 7.52 |
| CHEMBL888 | GEMCITABINE | 4.0 | 1 | 4.96 |
| CHEMBL185 | FLUOROURACIL | 4.0 | 1 | 4.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL385064 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL2203744 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL888 | GEMCITABINE | IC50 | = | 10988.0 | nM | 4.96 |
| CHEMBL185 | FLUOROURACIL | IC50 | = | 62303.0 | nM | 4.21 |