Assay Detail
Functional
CHEMBL4348093
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against VSV infected in African green monkey Vero cells assessed as plaque reduction preincubated for 10 mins inocula removed after 1 hr followed by overlaying with 2% methylcellulose and measured after 1 to 2 days by crystal violet staining based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vesicular stomatitis virus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Vesicular stomatitis virus (CHEMBL613739) ↗| Type | ORGANISM |
| Organism | Vesicular stomatitis virus |
Publication
Compounds based on 5-(perylen-3-ylethynyl)uracil scaffold: High activity against tick-borne encephalitis virus and non-specific activity against enterovirus A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.70 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3797928 | — | — | 1 | 8.70 |
| CHEMBL3798024 | — | — | 1 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3797928 | — | EC50 | = | 2.0 | nM | 8.70 |
| CHEMBL3798024 | — | EC50 | = | 2.0 | nM | 8.70 |