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Assay Detail

CHEMBL4349402

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of RANKL/tumour necrosis factor alpha-induced formation of osteoclasts (unknown origin) by tartrate-resistant acid phosphatase staining based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Not specified
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Review of the molecular mechanisms of Ganoderma lucidum triterpenoids: Ganoderic acids A, C2, D, F, DM, X and Y.
Liang C, Tian D, Liu Y, Li H, Zhu J, Li M, Xin M, Xia J.
Eur J Med Chem (2019) 174 : 130 -141
PubMed 31035236 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.52 4.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1099224 GANODERIC ACID DM 1 4.52
CHEMBL4567720 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1099224 GANODERIC ACID DM IC50 = 30000.0 nM 4.52
CHEMBL4567720 IC50 = 400000.0 nM -