Assay Detail
Functional
CHEMBL4349405
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human T9A4 cells assessed as reduction in cholesterol synthesis after 30 mins in presence of [14C]acetate, [14C]mevanolate, 24,25-dihydro-[24,25-3H2]lanosterol, [3-3H]lathosterol by acetate incorporation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Review of the molecular mechanisms of Ganoderma lucidum triterpenoids: Ganoderic acids A, C2, D, F, DM, X and Y.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.85 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1915760 | GANODERIC ACID Y | — | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1915760 | GANODERIC ACID Y | IC50 | = | 1400.0 | nM | 5.85 |