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Assay Detail

CHEMBL4349482

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of human K562 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type K562
Confidence 1 — Organism
Curated By Autocuration

Target

K562 (CHEMBL385)
Type CELL-LINE
Organism Homo sapiens

Publication

Targeting tropomyosin receptor kinase for cancer therapy.
Miao Q, Ma K, Chen D, Wu X, Jiang S.
Eur J Med Chem (2019) 175 : 129 -148
PubMed 31077998 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.29 7.29

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4589373 1 7.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4589373 IC50 = 51.4 nM 7.29