Assay Detail
Binding
CHEMBL4349875
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Inhibition of DGAT in CHOK1 cell microsomal fraction using [14C]palmitoyl-CoA as substrate measured after 15 mins TLC based method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cricetulus griseus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Inhibition of neutral lipid synthesis by avarols from a marine sponge.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.53 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL459814 | AVAROL | — | 1 | 4.70 |
| CHEMBL3965313 | — | — | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL459814 | AVAROL | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL3965313 | — | IC50 | = | 44300.0 | nM | 4.35 |