Assay Detail
Binding
CHEMBL4349876
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of African green monkey SOAT1 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Chlorocebus aethiops |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sterol O-acyltransferase 1 (CHEMBL3879850) ↗| Type | SINGLE PROTEIN |
| Organism | Chlorocebus aethiops |
Publication
Inhibition of neutral lipid synthesis by avarols from a marine sponge.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.79 | 4.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL459814 | AVAROL | — | 1 | 4.85 |
| CHEMBL3965313 | — | — | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL459814 | AVAROL | IC50 | = | 14200.0 | nM | 4.85 |
| CHEMBL3965313 | — | IC50 | = | 19200.0 | nM | 4.72 |