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Assay Detail

CHEMBL4350042

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Functional
Antiproliferative activity against human A549 cells after 24 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Autocuration

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Anti-proliferative activity and structure-activity relationship of honokiol derivatives.
Lin D, Yan Z, Chen A, Ye J, Hu A, Liu J, Peng J, Wu X.
Bioorg Med Chem (2019) 27 : 3729 -3734
PubMed 31278004 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.47 4.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL16901 HONOKIOL 1 4.47
CHEMBL570770 1 4.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL16901 HONOKIOL IC50 = 34100.0 nM 4.47
CHEMBL570770 IC50 = 34100.0 nM 4.47