Assay Detail
Functional
CHEMBL4350048
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Antiproliferative activity against human K562 cells by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anti-proliferative activity and structure-activity relationship of honokiol derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.50 | 4.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL570770 | — | — | 1 | 4.71 |
| CHEMBL16901 | HONOKIOL | — | 1 | 4.55 |
| CHEMBL562076 | — | — | 1 | 4.49 |
| CHEMBL562336 | — | — | 1 | 4.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL570770 | — | IC50 | = | 19700.0 | nM | 4.71 |
| CHEMBL16901 | HONOKIOL | IC50 | = | 28400.0 | nM | 4.55 |
| CHEMBL562076 | — | IC50 | = | 32600.0 | nM | 4.49 |
| CHEMBL562336 | — | IC50 | = | 54600.0 | nM | 4.26 |