Assay Detail
Functional
CHEMBL4351076
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against basophil derived from B-cell malignant patient by cell-titer aqueous one solution cell proliferation assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Evolution of PI3Kγ and δ Inhibitors for Inflammatory and Autoimmune Diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.77 | 7.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2216863 | DEZAPELISIB | 2.0 | 1 | 7.46 |
| CHEMBL2216870 | IDELALISIB | 4.0 | 1 | 6.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2216863 | DEZAPELISIB | IC50 | = | 35.0 | nM | 7.46 |
| CHEMBL2216870 | IDELALISIB | IC50 | = | 846.0 | nM | 6.07 |