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Assay Detail

CHEMBL4351107

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against human basophil cells after 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Evolution of PI3Kγ and δ Inhibitors for Inflammatory and Autoimmune Diseases.
Perry MWD, Abdulai R, Mogemark M, Petersen J, Thomas MJ, Valastro B, Westin Eriksson A.
J Med Chem (2019) 62 : 4783 -4814
PubMed 30582813 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.72 7.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4303323 ACALISIB 2.0 1 7.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4303323 ACALISIB IC50 = 19.0 nM 7.72