Assay Detail
Binding
CHEMBL4351163
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Binding affinity to ML-IAP-BIR domain (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Baculoviral IAP repeat-containing protein 7 (CHEMBL1075127) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibitor of Apoptosis Protein (IAP) Antagonists in Anticancer Agent Discovery: Current Status and Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.43 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3039522 | BIRINAPANT | 2.0 | 1 | 9.00 |
| CHEMBL2063869 | GDC-0152 | 1.0 | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3039522 | BIRINAPANT | Kd | = | 1.0 | nM | 9.00 |
| CHEMBL2063869 | GDC-0152 | Kd | = | 14.0 | nM | 7.85 |