Assay Detail
Binding
CHEMBL4351330
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at rat GluA2(Q) receptor expressed in Xenopus laevis oocytes assessed as induction of (S)-glutamate-induced channel current at -60 mV holding potential in presence of cyclothiazide by two-electrode voltage-clamp electrophysiology method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Use of the 4-Hydroxytriazole Moiety as a Bioisosteric Tool in the Development of Ionotropic Glutamate Receptor Ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.19 | 4.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4529665 | — | — | 1 | 4.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4529665 | — | EC50 | = | 65000.0 | nM | 4.19 |