Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4353792

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anticancer activity against human SK-N-MC cells assessed as inhibition of cell proliferation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SK-N-MC
Confidence 1 — Organism
Curated By Autocuration

Target

SK-N-MC (CHEMBL614163)
Type CELL-LINE
Organism Homo sapiens

Publication

The synthesis and anticancer activity of 2-styrylquinoline derivatives. A p53 independent mechanism of action.
Mrozek-Wilczkiewicz A, Kuczak M, Malarz K, Cieślik W, Spaczyńska E, Musiol R.
Eur J Med Chem (2019) 177 : 338 -349
PubMed 31158748 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.11 6.11

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL241908 1 6.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL241908 IC50 = 770.0 nM 6.11