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Assay Detail

CHEMBL4355048

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to HIV1 TAR RNA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Human immunodeficiency virus 1
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthetic small-molecule RNA ligands: future prospects as therapeutic agents.
Di Giorgio A, Duca M.
Medchemcomm (2019) 10 : 1242 -1255
PubMed 31534649 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 3 5.42 5.87

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1572 NETILMICIN 4.0 1 5.87
CHEMBL4474530 1 5.62
CHEMBL4442026 1 4.76

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1572 NETILMICIN Kd = 1350.0 nM 5.87
CHEMBL4474530 Kd = 2400.0 nM 5.62
CHEMBL4442026 Kd = 17500.0 nM 4.76