Assay Detail
Binding
CHEMBL4355991
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of RNA-dependent RNA polymerase in Zika virus PRVABC59 infected in African green monkey Vero cells infected with supernatants from virus-infected human SNB-19 cells treated with compound for 1 hr assessed as antiviral activity after 48 to 72 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Zika virus |
| Cell Type | Vero |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Drugs for the Treatment of Zika Virus Infection.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.06 | 8.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50588 | EMETINE | 4.0 | 1 | 8.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50588 | EMETINE | EC50 | = | 8.74 | nM | 8.06 |