Assay Detail
Binding
CHEMBL4356013
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Inhibition of Dengue virus 2 NS2B (48 to 95 residues)-NS3 (1 to 185 residues) expressed in Escherichia coli BL21 Rosetta (DE3) incubated for 30 mins followed by Abz-RRRRSAG-nTyr substrate addition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | dengue virus type 2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Drugs for the Treatment of Zika Virus Infection.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.75 | 5.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4437334 | — | — | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4437334 | — | IC50 | = | 1800.0 | nM | 5.75 |