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Assay Detail

CHEMBL4356058

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Activation of AMPK in African green monkey Vero cells infected with Zika virus PA259459 assessed as antiviral activity measured 24 hrs post infection by plaque assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Chlorocebus aethiops
Cell Type Vero
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Drugs for the Treatment of Zika Virus Infection.
Bernatchez JA, Tran LT, Li J, Luan Y, Siqueira-Neto JL, Li R.
J Med Chem (2020) 63 : 470 -489
PubMed 31549836 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.58 5.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3891221 1 5.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3891221 EC50 = 2600.0 nM 5.58