Assay Detail
Binding
CHEMBL4356079
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Inhibition of p97 (unknown origin) assessed as reduction in ATPase activity by biomol green reagent based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Transitional endoplasmic reticulum ATPase (CHEMBL1075145) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
p97: An Emerging Target for Cancer, Neurodegenerative Diseases, and Viral Infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.74 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4450581 | — | — | 1 | 8.15 |
| CHEMBL4476693 | — | — | 1 | 8.10 |
| CHEMBL3746912 | — | — | 1 | 6.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4450581 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL4476693 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL3746912 | — | IC50 | = | 110.0 | nM | 6.96 |