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Assay Detail

CHEMBL4356080

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Human Cytomegalovirus
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human betaherpesvirus 5
Confidence 1 — Organism
Curated By Autocuration

Target

Human betaherpesvirus 5 (CHEMBL371)
Type ORGANISM
Organism Human betaherpesvirus 5

Publication

p97: An Emerging Target for Cancer, Neurodegenerative Diseases, and Viral Infections.
Huryn DM, Kornfilt DJP, Wipf P.
J Med Chem (2020) 63 : 1892 -1907
PubMed 31550150 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.39 6.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2311578 1 6.89
CHEMBL182 GANCICLOVIR 4.0 1 5.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2311578 IC50 = 130.0 nM 6.89
CHEMBL182 GANCICLOVIR IC50 = 1300.0 nM 5.89