Assay Detail
Functional
CHEMBL4356310
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Anti-fibrinolytic activity in 5% human plasma in presence of fibrinogen by spectrophotometric method
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Plasma |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Fibrinolysis Inhibitors: Potential Drugs for the Treatment and Prevention of Bleeding.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 7.94 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4474501 | — | — | 1 | 8.22 |
| CHEMBL4457757 | — | — | 1 | 8.10 |
| CHEMBL4460436 | — | — | 1 | 8.10 |
| CHEMBL4535576 | — | — | 1 | 8.04 |
| CHEMBL4526972 | — | — | 1 | 8.00 |
| CHEMBL4518228 | — | — | 1 | 8.00 |
| CHEMBL4536269 | — | — | 1 | 7.96 |
| CHEMBL4578240 | — | — | 1 | 7.96 |
| CHEMBL4592797 | — | — | 1 | 7.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4474501 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL4457757 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL4460436 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL4535576 | — | IC50 | = | 9.1 | nM | 8.04 |
| CHEMBL4526972 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL4518228 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL4536269 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL4578240 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL4592797 | — | IC50 | = | 85.0 | nM | 7.07 |