Assay Detail
Binding
CHEMBL4356324
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human plasmin assessed as reduction in proteolysis activity in presence of fibrinogen after 90 mins by SDS-PAGE analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Fibrinolysis Inhibitors: Potential Drugs for the Treatment and Prevention of Bleeding.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.50 | 8.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2016877 | — | — | 1 | 8.51 |
| CHEMBL4589217 | — | — | 1 | 8.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2016877 | — | Ki | = | 3.1 | nM | 8.51 |
| CHEMBL4589217 | — | Ki | = | 3.3 | nM | 8.48 |