Assay Detail
Binding
CHEMBL4356344
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human plasmin using tosyl-Gly-Pro-Lys-pNA as substrate
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Fibrinolysis Inhibitors: Potential Drugs for the Treatment and Prevention of Bleeding.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.11 | 9.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3660186 | — | — | 1 | 9.60 |
| CHEMBL3660174 | — | — | 1 | 9.22 |
| CHEMBL3660177 | — | — | 1 | 8.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3660186 | — | Ki | = | 0.25 | nM | 9.60 |
| CHEMBL3660174 | — | Ki | = | 0.6 | nM | 9.22 |
| CHEMBL3660177 | — | Ki | = | 3.0 | nM | 8.52 |